By Curtis D. Klaassen
The such a lot entire, relied on reference textual content overlaying the entire span of clinical toxicology
A Doody's center name crucial buy for 2011!
"This reference stands on my own because the easy textual content within the box of toxicology. This authoritative reference is written by way of many amazing execs within the box, and provides transparent, concise descriptions of the major thoughts in toxicology. it truly is wide and whole, masking a extensive diversity of issues in adequate aspect. either as a reference and as an academic software, this e-book exceeds its target of serving as a reference for toxicologists, different scientists, and scholars of the self-discipline. three Stars."--Doody's assessment Service
Long tested because the finest within the box, Casarett & Doull's Toxicology equips you with an unsurpassed figuring out of contemporary toxicology, together with the rules, options, mechanisms, and modes of notion which are the basis of the self-discipline. the hot 7th variation good points is up-to-date all through and contains many new participants and new content material on chemical terrorism.
Read or Download Casarett & Doull's Toxicology: The Basic Science of Poisons (7th Edition) PDF
Similar toxicology books
"Based at the First foreign Symposium on Metals and Genetics held lately on the medical institution for ailing childrens in Toronto, Ontario, Canada. the single publication of its sort to target the results of metals on DNA. presents updated info on new advancements within the box and their wide-ranging implications.
At present serving as a source for the nationwide heart for Toxological Research in their paintings with the Gulf Coast oil spill, this booklet provides present learn performed essentially via the airforce at the poisonous results of JP-8 jet gas at the pulmonary, immune, dermal, and frightened systems. In all, the ebook considers thirteen toxicology experiences of importance, the result of that are presently shaping US armed providers coverage.
Scorched Earth is the 1st e-book to chronicle the consequences of chemical war at the Vietnamese humans and their atmosphere, the place, even this day, greater than three million people—including 500,000 children—are ill and loss of life from beginning defects, melanoma, and different health problems that may be at once traced to Agent Orange/dioxin publicity.
Genomic Biomarkers for Pharmaceutical improvement: Advancing custom-made wellbeing and fitness Care presents an in-depth evaluate of the nation of translational technological know-how throughout all phases of pharmaceutical improvement with a different specialize in customized wellbeing and fitness care. This ebook presents a whole photo of biomarker improvement and validation in a pharmaceutical surroundings whereas addressing the inherent demanding situations of concentrating on the right symptoms, biomarker robustness, regulatory hurdles, commercialization and lots more and plenty extra.
- Developmental Toxicology
- Handbook of Ecotoxicology (Second Edition)
- Formaldehyde: Chemistry, Applications and Role in Polymerization
- Principles of Biochemical Toxicology, Fourth Edition
Additional resources for Casarett & Doull's Toxicology: The Basic Science of Poisons (7th Edition)
Carson R: Silent Spring. Boston: Houghton Mifﬂin, 1962. Christison R: A Treatise on Poisons, 4th ed. Philadelphia: Barrington & Howell, 1845. Doll R, Peto R: The Causes of Cancer. New York: Oxford University Press, 1981. Donaldson HH: The history and zoological position of the albino rat. Natl Acad Sci 15:365–369, 1912. DuBois K, Geiling EMK: Textbook of Toxicology. New York: Oxford University Press, 1959. Gunther RT: The Greek Herbal of Dioscorides. New York: Oxford University Press, 1934. Guthrie DA: A History of Medicine.
Antag- 17 onistic effects of chemicals are often very desirable in toxicology and are the basis of many antidotes. There are four major types of antagonism: functional, chemical, dispositional, and receptor. Functional antagonism occurs when two chemicals counterbalance each other by producing opposite effects on the same physiologic function. Advantage is taken of this principle in that the blood pressure can markedly fall during severe barbiturate intoxication, which can be effectively antagonized by the intravenous administration of a vasopressor agent such as norepinephrine or metaraminol.
Serious lack of oxygen delivery to tissues after exposure to doses of methemoglobin-producing chemicals that would be harmless to individuals with normal NADH-cytochrome b5 reductase activity. Immediate versus Delayed Toxicity Immediate toxic effects can be deﬁned as those that occur or develop rapidly after a single administration of a substance, whereas delayed toxic effects are those that occur after the lapse of some time. Carcinogenic effects of chemicals usually have a long latency period, often 20 to 30 years after the initial exposure, before tumors are observed in humans.