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By Bin Wu, embriolog

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Fertil Steril 49(3):542-543, 1988. [64] Check JH: The multiple uses of ethinyl estradiol for treating infertility. Clin Exp Obst Gyn 2010;37:249-251. [65] Katsoff B, Check MD: Successful pregnancy in a 45-year-old woman with elevated day 3 serum follicle stimulating hormone and a short follicular phase. Clin Exp Obstet Gynecol 2005;32:97-98. [66] Check JH, Adelson H, Lurie D, Jamison T: The effect of the short follicular phase on subsequent conception. Gynecologic and Obstetric Investigation. 34:180-183, 1992.

Thus there may have been some bias with the normal FSH group since our IVF center attracts some difficult cases who failed several previous IVF cycles in other centers, while the high FSH group may never have any previous IVF cycles being rejected because of their high day 3 FSH levels. 1 % SAB/clin. 9 Table 4. 0 % SAB/clin. 0 Table 5. Pregnancy rates by age and FSH levels – older group 11. Other studies using mild stimulation for diminished oocyte reserve Not all studies agree that mild stimulation is the key for achieving a reasonable pregnancy rate in “poor responders”.

High dosage FSH stimulation according to the degree of ovarian oocyte reserve. 2. 1 Oogenesis and hormone function on ovarian A necessary factor for the development of antral follicles into dominant follicles is a hormone called the follicle stimulating hormone (FSH). In those normal ovulating women, a complex interaction occurs between the FSH and granulosa theca cells of these follicles which are 22 Advances in Embryo Transfer associated with up and down regulation of FSH receptors on these granulosa-theca cells.

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